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Language English Format Still image Identifier MS_6689703_161_007 Subject Christmas, holiday, winter, gift, carton, Santa Claus, pipe, tobacco

Our central character in this backstory is that of the crews project manager, who forged a loving bond with a West African worker named Adam

Therefore, considering that there is a higher exposure to some cigarette components in that area, and that these processes are important in the pathophysiology of CD, the three hypotheses converge to help explain the increased risk of developing ileal CD in smokers

Moreover, our data show that similar mitochondrial changes are present in bronchial epithelium from severe ex-smoking COPD patients in comparison to healthy controls, with depletion of cristae, increased branching, elongation and swelling of the mitochondria, increased Mn-SOD, PINK1 and PPARGC1, but not OPA1 mRNA expression and increased OXPHOS Complex VF1 levels