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These associations are thought to reflect the co-morbidity of smoking and vascular, respiratory, and substance use/psychological conditions

The last flu pandemic occurred in 1968/69 and reached a high of over 700 cases per 100,000 people in the population

The differential diagnosis included herpetic ulceration, erythema multiforme, immunobullous disease, syphilis infection and erosive lichen planus

The data was originally collected in 2015 at a time when many vaping devices involved larger volume tank systems, refilled by users with separately purchased oil, rather than the more ubiquitous smaller volume pods we see today