current cigarette smoking among adults in the united states — States, 2016 Figure 13.11, Trends in prevalence

While nicotine stomatitis wont directly cause cancer, chronic tobacco use, in general, can Smokers palate is not a common side effect of smoking but there is always a possibility that it will develop if you smoke heavily

Summary-level Mendelian randomisation of effect of bipolar disorder on smoking The MR analyses of the effect of liability to bipolar disorder on risk of smoking initiation (beta IVW = 0.008, 95% CI 0.026 to 0.009, P = 0.35), lifetime smoking (beta IVW = 0.001, 95% CI 0.032 to 0.030, P = 0.95) and smoking cessation (OR IVW = 0.003, 95% CI 0.9811.014, P = 0.74) revealed no evidence of a causal effect (Table 1, supplementary Figs 46, 1012, 1618)

The effects of beta-blocker use on cancer prognosis: a meta-analysis based on 319,006 patients

svold BO, Bjrngaard JH, Carslake D, et al