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Data from animal studies also suggests that R-nicotine may metabolize more quickly than S-nicotine 18

However, this is far more likely to be as a result of your returning appetite, repaired taste buds, decreased metabolism and water retention which can occur from quitting cigarettes not from vaping itself

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Nicotine withdrawal (with its craving and nicotine-specific withdrawal symptoms) and consumption (with abusive behavior and addiction) are interwoven in a self-perpetuating cycle that deepens over time