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Metabolic Processing Differences: Smoking delivers delta-9 THC directly to cannabinoid receptors, while edibles convert THC into 11-hydroxy-THC through liver metabolism
For example, the US Surgeon General (Office of the Surgeon General1988) reported a range of peak puff flow rates of 28 to 48 mL/s on the basis of data obtained from 5 studies (Gritz et al.1983;Guillerm and Radziszewski
Since many smoking cessation methods depend on nicotine such as nicotine patches and e-cigarettes, these may not be as effective to women as they are to men
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