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Third, the temporal scope of the study only captures information between 2019 and 2021, thereby missing long-term trends, and unmeasured factors, such as user characteristics, socio-cultural and geographical contexts, or contemporaneous events in the e-cigarette market

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The main risk of long-term use is a continued dependence on nicotine, but since nicotine gum lacks the harmful chemicals found in cigarettes, the risks are significantly lower