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The FDA says the applications for Fontem's products were rejected partly because the company failed to present "sufficient evidence regarding design features, manufacturing, and stability." But the FDA also says "the applications did not demonstrate that the potential benefit to smokers who switch completely or significantly reduce their cigarette use would outweigh the risk to youth." The latter concern is puzzling on its face

Here is a list of some of the chemicals found in unfiltered cigarette smoke besides carbon monoxide: hydroquinone, methacrolein, methyl alcohol, methylamine, nickel compounds, pryidine, carbon dioxide, crotonomitrile, dimethylamine, endrin, ethylamine, furfural, cadmium, methyl nitrite, ammonia