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By using the method of Peto and colleagues (1992) or one of its variants to derive estimates of total smoking-related mortality from data on lung cancer mortality, it is possible to compare smoking-related deaths across countries and through time and thus to estimate the role of smoking in the divergence in life expectancy trends

[28] Exposure to Gutka tends to be highest in saliva and urine as evaluated by measuring 8-OHdG in DNA