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A recent study by Salaam Bombay Foundation of 306 youth in the city showed that 80% of e-cigarette users had not used any tobacco product previously, underlining that ENDS was becoming a potential gateway to tobacco use.
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We also observed a significant downregulation of 7nAChR expression in 7nAChR siRNA-transfected hASM cells when exposed to nicotine, confirming the knockdown of 7nAChR due to attenuation of nicotinic activity (Fig
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