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Specifically, given the known acute effect of 4-HNE in activating uncoupling proteins to lower mitochondrial membrane potential, the lower abundance of ANT and UCP3 observed after 8 mo of cigarette smoke exposure might represent a late adaptation to restore proton leak when the mitochondrial membrane potential has reached a critical value that may compromise the rate of ATP synthesis

METHODS Setting The setting for the data collection included the two largest government-owned obstetrics and gynecology clinics located in Cluj-Napoca, Romania: Clinica Obstetrica-Ginecologie I and Clinica Obstetrica-Ginecologie II

Public Health 17 Baldassarri, S

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