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The minimum cluster size required for corrected significance was determined with a Monte Carlo simulation of 1,000 iterations (Slotnick et al

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Nicotine withdrawal symptoms include: Intense cravings Anxiety and irritability Restlessness and difficulty concentrating Insomnia Constipation or diarrhea Toxic Substances Its true that e-cigarettes dont have as many chemicals as traditional tobacco products, but that doesn't mean theyre safe