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These include liver and colorectal cancer, diabetes mellitus, ectopic pregnancy, erectile dysfunction, age-related macular degeneration, orofacial clefts in newborns (as a result of maternal smoking), rheumatoid arthritis, and health problems such as inflammation and impaired immune functioning

The analysis was performed using FastTree (version 2.1.10) software 21 , ML trees were constructed, and visualization was performed using R software

[28] Interest in Cuban cigars has also influenced one of Cuba's tourism industries