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Trouble sleeping and restlessness Insomnia, fatigue, and restlessness are all common side effects of nicotine withdrawal, according to a 2019 review of literature

Although more nicotine is extracted from the lozenge than the NP (100% vs 62%), the similar C max and AUC 0-T values observed for the NP and lozenge suggests that absorption of released nicotine is greater from the pouch than the lozenge

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It concluded that while research was still trying to catch up with the relatively new range of vaping products on the market, there was already cause for serious concern