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The poisoning of Brock may have opened up the floodgates of Walt's villainous actions, but from nearly taking a young boy's life to using it to manipulate Jesse into committing another murder to using Gus's death to solidify his empire, Walt poisoning Brock remains his most heinous act on Breaking Bad

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You dont have those types of side effects with a vaccine approach because the vaccine produces antibodies leveraging your own immune system to produce antibodies