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Leading manufacturers are acquiring regional or niche tobacco brands to strengthen market share, diversify offerings, and integrate innovative production technologies

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[140] A 2017 study found that "The maximum detected concentrations of benzene, methanol, and ethanol in the samples were higher than their authorized maximum limits as residual solvents in pharmaceutical products." [140] Trace amounts of toluene [114] and xylene have been found in the e-cigarette vapor