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At lower smoking rates, there is some evidence of appetite suppression from nicotine and increased metabolic rate

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Caffeine is a stimulant, meaning that it makes you feel more alert, while alcohol is a depressant that slows everything down in the central nervous system

To overcome these limitations, we developed a whole CS extract (WCSE) model that combines both particulate and gaseous components to more accurately represent the physiological complexity of a chronic exposure platform