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Here we will take the 3% and 5% as example: Nicotine volume of a BC5000 3%: 13ml * 30mg/ml = 390mg 5%: 13ml * 50mg/ml = 650mg Compare to traditional cigarette: 3% BC5000: 390mg equivalent to approximately 200-400 cigarettes or about 10-20 packs 5% BC5000: 650mg equivalent to approximately 400-600 cigarettes or about 20-30 packs Count with Puffs True to its name, the BC5000 provides approximately 5000 puffs per device when used normally

This creates a perfect storm for liver necrosis, even at dosages that would otherwise be considered therapeutic

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However, for the cases, the inquiry occurred before the diagnosis of Type 1 DM to explore the association with SHS