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MERV 13 in the HVAC for the whole house, plus a portable HEPA cleaner in a clean room (usually the bedroom) for concentrated protection where you spend the most time

Long-term exposure of TRAP PM2.5, or fine PM including diesel emissions, has been linked to an increased lung cancer risk, lung cancer mortality and cardiopulmonary disease, with significantly increased risk among truck drivers and transportation workers [37,38,39]

But long-term use of these medicines can have serious side effects, such as weight gain, diabetes, osteoporosis, cataracts and a higher risk of infection

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