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Freebase nicotine is the 'go-to' nicotine in most vape juices, and nicotine replacement therapies such as gums, patches and sprays

Symptoms include: Tremors Constricted pupils Drooling Auditory and visual hallucinations Excitement Vomiting and diarrhea Twitching, possibly progressing to seizures Racing heart rate but slow heart rate with small doses High blood pressure but at higher doses, there is a circulatory collapse It is easy to confuse nicotine poisoning with other poisonings such as strychnine, chocolate, organophosphate insecticides, and certain molds

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And, despite the need for more research on e-cigarettes, it is becoming clear, due to the recent cases of EVALI, that using e-cigarettes has health consequences beyond those of nicotine alone