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Interestingly, those reporting dual use indicated greater importance of quitting all tobacco or nicotine products, yet they also exhibited lower confidence in achieving this goal compared to participants exclusively using e-cigarettes

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For example, nicotine-mediated protection occurs independently of GPR15, suggesting the presence of parallel signaling pathways (Supplementary Fig

In Japan, male smokers are 4.4 times more likely to get lung cancer than non-smokers and female smokers are 2.8 times more likely to get lung cancer than non-smokers