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Conclusions In conclusion, we explored the accuracy of the 2017 nosology for the cEDS diagnosis in a cohort of patients from different ages and sexes with a defined molecular defect and tried to offer a full picture of the multisystemic involvement and some views on the natural history of this condition

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As soon as smoke reaches your nose, the normally active hairs freeze up, allowing mucus to build in the sinuses, too, where it makes you vulnerable to infection and inflammation