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This work was supported by the National Institutes of Health, the UCLA Medical Scientist Training Program, a UCLA David Geffen School of MedicineBroad Stem Cell Research Center COVID-19 Research Award, the California Institute for Regenerative Medicine, the UCLA Clinical and Translational Science Institute (supported by National Institutes of Health's National Center for Advancing Translational Sciences), the Tobacco-Related Disease Research Program, and the Ablon Scholars Program at the UCLA Jonsson Comprehensive Cancer Center and UCLA Broad Stem Cell Research Center.

They have been promoted as a way to help quit smoking or vaping however studies show that smokers end up becoming addicted to both pouches and smoking or vaping

However, the World Health Organisation (WHO) has declared that e-cigarettes are undoubtedly harmful to health and that they are not safer alternatives to regular cigarettes

FDA approves sale of reduced-nicotine cigarettes Giving up cigarettes is easier when they contain less nicotine, a chemical stimulant that's highly addictive