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Freezing the chewing tobacco leaves may preserve them for a long time, but it can actually negatively impact their quality

Argentine authorities present this development as a response to the failure of prohibition, arguing that these products continued to circulate widely through informal channels without health or tax controls

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However, these changes were intended to address the concerns of individuals who showed harmful smoking patterns not yet diagnosed as dependent based on DSM-IV, and to improve sensitivity, specificity, and predictive value of poor results under the DSM-IV ND criteria [1820]