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Here we demonstrated that chronic nicotine exposure increases the tonic activity of VTA DA neurons and reduces undirected exploration to favor exploitation, with mice focusing on the most valuable options at the expense of information gathering

People who are already using it, its another reason to keep using it. Longtime cigarette smoker Robin Harkness-Magnuson is looking at other options to avoid the added expense

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Culturing the cells in a Petri dish and wafting smoke over them doesnt work well, because that setup cant replicate the dynamic environment of a real lung where cells move with every breath