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Even though the Haudenosaunee had plenty of meat, fish and fowl available to them in the wild, they lived mainly on their own cropscorn, beans and squash, which were called "The Three Sisters." The men cleared the land for planting, chopping down trees and cutting the brush, while the women planted, tended and harvested the crops

Wagener, founding director of The Center for Tobacco Research (CTR) at The Ohio State University Comprehensive Cancer Center Arthur G

Mol Cell Biochem 279:105112 Nesnow S, Roop B, Lambert G et al (2002) DNA damage induced by methylated trivalent arsenicals is mediated by reactive oxygen species

The slower burn rate of pipe tobacco also allows more flavor expression