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[4] Merit had a 3 } : Cite uses generic title (help) "Ingredients in Cigarettes - Merit The Companies - Philip Morris"

As with most addictive substances, nicotine activates the brains reward circuits and also increases levels of a chemical messenger in the brain called dopamine , which reinforces rewarding behaviors

Conversely, if the e-liquid has a dosage that's too high for you, you risk overdosing, which can lead to various symptoms such as bad coughs, headaches and nausea

But again, it's not evenly distributed, with much higher smoking rates in minorities, LGBTQ, those with comorbid psychiatric disease, substance abuse, etc