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++ For ACOs that select preliminary prospective assignment with retrospective reconciliation, limit the distribution of the standardized written beneficiary information notification to beneficiaries who are more likely to be assigned to the ACO, when compared to the beneficiaries who must receive the written notification under current regulations (section III.G.8.b of this proposed rule)

If youth use becomes problematic, I think the FDA now has a stronger legal basis to take action on marketing of authorized products and removing unauthorized products in the market.

So what distinguishes, for example, Nexone