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Geographical differences in the trends were also noted, with Latin America and high-income North America, Australia, Colombia, and Canada showing the greatest decline, and middle-SDI regions, especially East Asia, showing a slight upward trend

Binmadi N, et al

We are limiting Medicare payment to OTPs for nalmefene to one add-on code every 30 days, however, we will allow exceptions to this limit in the case where the beneficiary overdoses and uses the initial supply of nalmefene dispensed by the OTP, to the extent that it is medically reasonable and necessary to furnish additional doses of nalmefene

Reynolds Smith objects to health advocates referring to the products as candy, saying that will only pique the interest of children