Despite its classification as a highly addictive substance affecting approximately 50 million people in the U.S., tobacco is often excluded from formal substance use treatment plans
CONCLUSIONS Our findings support a model in which cigarette smoke exposure is associated with MKK3/p38 MAPK activation and PRKN Ser131 phosphorylation, accompanied by impaired PRKN-dependent mitophagy and increased epithelial senescence markers in vitro and in vivo
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And when advising people over 50 about reducing driving risks related to their cannabis use, she said, health care providers and public health agencies may want to focus on strategies like using cannabis at times when theyre unlikely to need to drive, such as before bedtime, and the importance of planning ahead for safe transportation via a designated driver or ride share service