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They also found increased levels of CD4+ T cells, a type of white blood cell, which were releasing a pro-inflammatory protein called interferon-gamma

In addition, genes upregulated by smoking among apical epithelial cell types ( KRT8 high , mucus secretory, and ciliated) were enriched for mucus secretory cell markers, supporting an increase in the secretory activity of these cells (Fig

The percentage also increased among adults aged 26 or older, from 12.3 percent (or 27.1 million people) in 2021 to 15.1 percent (or 34.3 million people) in 2024 ( Table A.6B )