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Methods Human subjects The human study was reviewed and approved by the institutional review board of Zhejiang Provincial Peoples Hospital (2021QT130)

The chemicals present in tobacco can disrupt the normal functioning of reproductive hormones, leading to various complications

Furthermore, studies focusing on the hormonal changes that occur after quitting smoking and the subsequent effects on testosterone levels are warranted

In the non-treatment extension of the postmarketing neuropsychiatric safety outcomes trial that assessed CV safety (8), the most common adverse events in subjects treated with varenicline and occurring up to 30 days after last dose of treatment were similar to those observed in premarketing studies