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[26] Roger Ebert, who gave the original film a mixed review, described the sequel as "terrific entertainment", despite noting substantial credibility problems with the plot

Specifically, the risk increases were as follows: Stage I Lung Cancer: 3.3 times more likely to develop a second cancer Bladder Cancer: 3.7 times more likely to develop a second cancer Head and Neck Cancers: 4.5 times more likely to develop a second cancer Kidney Cancer: 5.3 times more likely to develop a second cancer Current smokers who smoked fewer than 20 cigarettes per day and former smokers who had quit before their first cancer diagnosis also had an elevated risk of developing a second primary smoking-associated cancer compared to survivors who never smoked (although risks decreased with the number of years since smoking cessation)

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Collectively, these findings underscore that cigarette smoking is not only associated with an increased risk of developing PBC but also accelerates disease progression, worsens fibrosis, elevates HCC risk, and contributes to poorer long-term outcomes