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However, epidemiological studies of environmental exposures in relation to epigenetic patterns in PD are only beginning to emerge

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Mendelian randomisation of effect of smoking on bipolar disorder When comparing the current findings to those of a previous study evaluating the relationship between smoking and other severe mental illness, Reference Wootton, Richmond, Stuijfzand, Lawn, Sallis and Taylor12 the effect sizes we found are comparable to those testing lifetime smoking and smoking initiation as a risk factor for schizophrenia and major depressive disorder

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