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Smokers have a higher requirement for vitamins and minerals than non-smokers Antioxidants taken in supplement form can become provident and increase the cancer risk in smokers Antioxidants taken in supplement form, particularly vitamins A and E, can become provident and increase the cancer risk in smokers. So when it comes to vitamin C, which smokers are particularly deficient in, rather than taking supplements they should make sure to get wide range of fruits and vegetables in their diet