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11 OC-SCC is preceded by leukoplakia (white), erythroplakia (red), or erythroleukoplakia mixed/speckled-type lesions that present on the tongue, floor of the mouth, buccal mucosa, labial mucosa, retromolar trigone, and soft palate

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Conversely, a pharmacologic dose of either nicotinic acid or nicotinamide was able to increase NAD and poly ADP-ribose in bone marrow and decrease the development of leukemia in rats (52)