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Indirect costs, such as healthcare expenses and lost productivity, also contribute to the overall financial burden of smoking

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Nicotine, the primary addictive component in tobacco, stimulates the release of dopamine, creating pleasurable sensations that reinforce continued use

By varying main stream smoking patterns and flow rates of side stream and dilution air, the system can generate a wide range of cigarette smoke mixtures with various main stream to side stream ratios and overall smoke concentrations